Effects of Shiatsu on the Health-Related Quality of Life of a Person with Secondary Progressive Multiple Sclerosis: a mixed methods N-of-1 trial within a whole systems research case study
By Stergios Tsiormpatzis - Online MSc - Advanced Oriental Medicine
Abstract
Background
MS is a chronic neurological disorder with high prevalence in Finland. Most people with MS will develop Secondary Progressive MS (SPMS) over the years. People with MS report lower than the average Health-Related Quality of Life (HRQoL) and use CAM for their symptoms. Interventions of personalised nature like shiatsu have an insufficient evidence base. The n-of-1 trial is a promising study design for personalised interventions in chronic conditions yet it has not been used a lot in CAM research.
Aims and Objectives
The aim was to investigate if shiatsu affects the HRQoL of a person with SPMS. Objectives were to design and implement a mixed methods n-of-1 trial within a whole systems research case study and to reflect on the implementation and the appropriateness of the design.
Methodology
Six-periods counterbalanced mixed methods n-of-1 trial within a whole systems research case study was used. The short version of the MSQLI, data collected from the semi-structured interview and case notes were used to assess the effect of the treatment. Structured personal reflection was included.
The collected data analysed quantitatively and qualitatively and synthesised as a descriptive case study.
Findings
The study was able to document improvements in spasticity, bowel function, sleep and relaxation, fatigue and pain. No adverse events occurred. Preliminary estimations of the onset and wash-out of shiatsu effects were inferred. Advantages and drawbacks of the design are discussed to improve future applicability.
Conclusion
Shiatsu was able to improve some domains of the HRQoL of a person with SPMS. It was a safe treatment with no adverse events. Mixed methods n-of-1 trial within a whole systems research case study was an appropriate design for the study.
